| Food & Diet

4 Potent Benefits Of Rutaecarpine

By Jayton Miller

Rutaecarpine has long been used in traditional Chinese medicine to counteract the effects of caffeine, aid digestion problems, counter infection and maintain body weight. The benefits of rutaecarpine are far reaching, and not well known.

It is a plant native to China and Korea that grows berries known as "fruits of evodia," or evodia fructae. Rutaecarpine is a compound that is isolated from the berries produced by the evodia rutaecarpa plant.


Other Names for Rutaecarpine:

Rutaecarpine is also referred to as evodia, evodia extract, evodiae fructus, evodia fruit, and evodia rutaecarpa.

Benefits Of Rutaecarpine:

While the research on the effects of rutaecarpine on the human body is still somewhat limited, it is suggested that the chemical has a number of potential benefits, including the following:

Weakens The Effects Of Caffeine

Rutaecarpine has been shown to metabolize caffeine, causing it to be excreted from the body quickly and reducing its effects on the body. With quick elimination of caffeine, any unpleasant side effects of caffeine can subside, including sleeplessness and jitters.

May Help Kill Off Cancer Cells

Some studies suggest that rutaecarpine shows promise as an anti-cancer agent by killing cancer cells and inhibiting the growth of tumor cell lines, particularly for cervical cancer, melanoma and cancer of the thyroid.

May Help Reduce Inflammation

Rutaecarpine has long been used for its anti-inflammatory properties thanks to the actions of certain constituents of the evodia rutaecarpa plant.

May Help Burn Body Fat

Rutaecarpine has been investigated as a fat burner and therefore has been touted as a potentially effective weight loss agent. In animal studies, it appears to make subjects feel hotter and expends heat more efficiently, which has a fat-burning effect.

Other potential benefits of rutaecarpine may include it helping with the following, though evidence to support such claims is very limited:

  • Diarrhea
  • Nausea
  • Vomiting
  • Lack of Menstruation
  • Stomach Ulcers
  • Gastroesophageal Reflux Disease
  • Fluid Retention

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How To Use Rutaecarpine:

Currently, there isn't enough scientific data on rutaecarpine to determine an appropriate dose for the chemical. That said, dosing should be based on a number of factors including the user's:

  • Age
  • Weight
  • Health
  • Use of Medications
  • Presence of Illness

It's also important to follow manufacturers' suggestions when dosing, so be sure to follow specific directions on product labels and always consult with a doctor or pharmacist before using rutaecarpine or any other natural supplement.

Certain individuals should not take rutaecarpine, including pregnant or breastfeeding women, as there is insufficient information showing whether or not the chemical is safe for both mother and baby.

Further, those who are scheduled for surgery in the near future should not take rutaecarpine because of its link to slowed blood clotting. There may be a concern that rutaecarpine could increase the risk of bleeding during and after surgery.

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Learn More: What Is Magnesium Bicarbonate

Interactions With Medications:

Caution should be taken when using rutaecarpine while taking other medications as the chemical may interact with them and reduce their effect, such as blood clotting medication. It's important to speak with a healthcare provider before introducing rutaecarpine to the body when in the presence of other medications.


There may be some evidence to suggest that rutaecarpine can help reduce the jittery effects of caffeine, help with weight loss, and aid with digestive issues. But the science behind the chemical is limited to just animal studies.

More human studies are needed to solidify rutaecarpine benefits on the human body. As with any other supplement or herbal product, it's important to consult with a physician or health care practitioner first.